UNIT 1.1 The Importance of Biological Databases in Biological Discovery

  1. Andreas D. Baxevanis

Published Online: 1 SEP 2009

DOI: 10.1002/0471250953.bi0101s27

Current Protocols in Bioinformatics

Current Protocols in Bioinformatics

How to Cite

Baxevanis, A. D. 2009. The Importance of Biological Databases in Biological Discovery. Current Protocols in Bioinformatics. 27:1.1.1–1.1.6.

Author Information

  1. Bethesda, Maryland

Publication History

  1. Published Online: 1 SEP 2009
  2. Published Print: SEP 2009

This is not the most recent version of the article. View current version (1 JUN 2011)


Biological databases play a central role in bioinformatics. They offer scientists the opportunity to access a wide variety of biologically relevant data, including the genomic sequences of an increasingly broad range of organisms. This unit provides a brief overview of major sequence databases and portals, such as GenBank, the UCSC Genome Browser, and Ensembl. Model organism databases, including WormBase, the Arabidopsis Information Resource (TAIR), and those made available through the Mouse Genome Informatics (MGI) resource are also covered. Non-sequence-centric databases such as Online Mendelian Inheritance in Man (OMIM), the Protein Data Bank (PDB), MetaCyc, and the Kyoto Encyclopedia of Genes and Genomes (KEGG) are also discussed. Curr. Protoc. Bioinform. 27:1.1.1-1.1.6. © 2009 by John Wiley & Sons, Inc.


  • biological database;
  • sequence database;
  • structure database;
  • model organisms;
  • biological pathways