Unit

UNIT 1.7 Searching the Mouse Genome Informatics (MGI) Resources for Information on Mouse Biology from Genotype to Phenotype

  1. David R. Shaw

Published Online: 1 MAR 2009

DOI: 10.1002/0471250953.bi0107s25

Current Protocols in Bioinformatics

Current Protocols in Bioinformatics

How to Cite

Shaw, D. R. 2009. Searching the Mouse Genome Informatics (MGI) Resources for Information on Mouse Biology from Genotype to Phenotype. Current Protocols in Bioinformatics. 25:1.7:1.7.1–1.7.14.

Author Information

  1. MGI User Support, The Jackson Laboratory, Bar Harbor, Maine

Publication History

  1. Published Online: 1 MAR 2009
  2. Published Print: MAR 2009

Abstract

The Mouse Genome Informatics (MGI) resource provides the research community with access to information on the genetics, genomics, and biology of the laboratory mouse. Core data in MGI include gene characterization and function, phenotype and disease model descriptions, DNA and protein sequence data, gene expression data, mammalian orthologies, SNPs and PCR polymorphisms, mapping data, and links to other bioinformatics databases. Data integration is supported through the use of standardized nomenclature, and through the use of controlled vocabularies such as the mouse Anatomical Dictionary, the Mammalian Phenotype Ontology, and the Gene Ontologies. MGI extracts and organizes data from primary literature. MGI data are shared with and widely displayed from other bioinformatics resources. The database is updated nightly with curated annotations, and regularly adds new datasets. This unit provides a guide to using the MGI bioinformatics resource. Curr. Protoc. Bioinform. 25:1.7.1-1.7.14. © 2009 by John Wiley & Sons, Inc.

Keywords:

  • mouse;
  • genome;
  • genes;
  • phenotypes;
  • expression;
  • alleles;
  • function