UNIT 1.8 Searching WormBase for Information about Caenorhabditis elegans

  1. Erich M. Schwarz1,
  2. Paul W. Sternberg2

Published Online: 1 JUL 2006

DOI: 10.1002/0471250953.bi0108s14

Current Protocols in Bioinformatics

Current Protocols in Bioinformatics

How to Cite

Schwarz, E. M. and Sternberg, P. W. 2006. Searching WormBase for Information about Caenorhabditis elegans. Current Protocols in Bioinformatics. 14:1.8:1.8.1–1.8.43.

Author Information

  1. 1

    California Institute of Technology, Pasadena, California

  2. 2

    Howard Hughes Medical Institute, California Institute of Technology, Pasadena, California

Publication History

  1. Published Online: 1 JUL 2006
  2. Published Print: JUN 2006


WormBase is the major public biological database for the nematode Caenorhabditis elegans. It is meant to be useful to any biologist who wants to use C. elegans, whatever his or her specialty. WormBase contains information about the genomic sequence of C. elegans, its genes and their products, and its higher-level traits such as gene expression patterns and neuronal connectivity. WormBase also contains genomic sequences and gene structures of C. briggsae and C. remanei, two closely related worms. These data are interconnected, so that a search beginning with one object (such as a gene) can be directed to related objects of a different type (e.g., the DNA sequence of the gene or the cells in which the gene is active). One can also perform searches for complex data sets. The WormBase developers group actively invites suggestions for improvements from the database users. WormBase's source code and underlying database are freely available for local installation and modification.


  • Caenorhabditis elegans;
  • WormBase;
  • nematode;
  • genomic annotation;
  • gene expression pattern;
  • RNAi;
  • neuronal connectivity