Unit

UNIT 2.9 Using CorePromoter to Find Human Core Promoters

  1. Michael Q. Zhang

Published Online: 1 JUL 2005

DOI: 10.1002/0471250953.bi0209s10

Lab Protocol Title

Current Protocols in Bioinformatics

Current Protocols in Bioinformatics

Additional Information

How to Cite

Zhang, M. Q. 2005. Using CorePromoter to Find Human Core Promoters. Current Protocols in Bioinformatics. 10:2.9:2.9.1–2.9.10.

Author Information

  1. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York

Publication History

  1. Published Online: 1 JUL 2005
  2. Published Print: JUN 2005
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Abstract

The CorePromoter program is very useful for identification of transcriptional start sites (TSS) and core promoter regions when 5′-upstream genomic DNA sequences of human genes are available. It is very simple to use and can be accessed either through the Web or after downloading to a local computer. The protocols in this unit introduce its basic methodology and discuss how to apply it to a sample problem in conjunction with other gene-finding programs.

Keywords:

  • Core promoter;
  • QDA;
  • TSS;
  • Transcriptional Initiation Site;
  • PIC;
  • Pre-Initiation Complex
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