UNIT 2.9 Using CorePromoter to Find Human Core Promoters

  1. Michael Q. Zhang

Published Online: 1 JUL 2005

DOI: 10.1002/0471250953.bi0209s10

Current Protocols in Bioinformatics

Current Protocols in Bioinformatics

How to Cite

Zhang, M. Q. 2005. Using CorePromoter to Find Human Core Promoters. Current Protocols in Bioinformatics. 10:2.9:2.9.1–2.9.10.

Author Information

  1. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York

Publication History

  1. Published Online: 1 JUL 2005
  2. Published Print: JUN 2005


The CorePromoter program is very useful for identification of transcriptional start sites (TSS) and core promoter regions when 5′-upstream genomic DNA sequences of human genes are available. It is very simple to use and can be accessed either through the Web or after downloading to a local computer. The protocols in this unit introduce its basic methodology and discuss how to apply it to a sample problem in conjunction with other gene-finding programs.


  • Core promoter;
  • QDA;
  • TSS;
  • Transcriptional Initiation Site;
  • PIC;
  • Pre-Initiation Complex