Unit
UNIT 2.15 DNA Motif Databases and Their Uses
Published Online: 3 SEP 2015
DOI: 10.1002/0471250953.bi0215s51
Copyright © 2013 John Wiley & Sons, Inc. All rights reserved.
Lab Protocol Title
Current Protocols in Bioinformatics
Additional Information
How to Cite
2015. DNA motif databases and their uses. Curr. Protoc. Bioinform. 51:2.15.1-2.15.6. doi: 10.1002/0471250953.bi0215s51
Publication History
- Published Online: 3 SEP 2015
- Abstract
- Article
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- References
Abstract
Transcription factors (TFs) recognize and bind to specific DNA sequences. The specificity of a TF is usually represented as a position weight matrix (PWM). Several databases of DNA motifs exist and are used in biological research to address important biological questions. This overview describes PWMs and some of the most commonly used motif databases, as well as a few of their common applications. © 2015 by John Wiley & Sons, Inc.
Keywords:
- transcription factors;
- DNA motifs;
- position weight matrices;
- binding site predictions
