UNIT 5.2 FAMS and FAMSBASE for Protein Structure
Published Online: 1 FEB 2004
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Bioinformatics
How to Cite
Umeyama, H. and Iwadate, M. 2004. FAMS and FAMSBASE for Protein Structure. Current Protocols in Bioinformatics. 4:5.2:5.2.1–5.2.16.
- Published Online: 1 FEB 2004
- Published Print: DEC 2003
The computer program FAMS (Full Automatic Modeling System) performs homology modeling of protein structures by means of an algorithm consisting of database searches and simulated annealing. FAMS produces a model in which the torsion angles of the backbone and sidechains are highly accurate. The operations of the FAMS algorithm are fully automated, and, therefore, special knowledge, techniques or experience are not required in order to obtain a biologically worthwhile protein structure.