Unit

UNIT 7.4 DRAGON and DRAGON View: Information Annotation and Visualization Tools for Large-Scale Expression Data

  1. Christopher M.L.S. Bouton1,
  2. Jonathan Pevsner2

Published Online: 1 AUG 2003

DOI: 10.1002/0471250953.bi0704s02

Current Protocols in Bioinformatics

Current Protocols in Bioinformatics

How to Cite

Bouton, C. M. and Pevsner, J. 2003. DRAGON and DRAGON View: Information Annotation and Visualization Tools for Large-Scale Expression Data. Current Protocols in Bioinformatics. 2:7.4:7.4.1–7.4.22.

Author Information

  1. 1

    LION Bioscience Research, Cambridge, Massachusetts

  2. 2

    Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Baltimore, Maryland

Publication History

  1. Published Online: 1 AUG 2003
  2. Published Print: MAY 2003

Abstract

The Database Referencing of Array Genes ONline (DRAGON) database system consists of information derived from publicly available databases including UniGene, SWISS-Prot, Pfam, and the Kyoto Encyclopedia of Genes and Genomes (KEGG). Through a Web-accessible interface, the DRAGON Annotate tool rapidly supplies information pertaining to a range of biological characteristics of all the genes in any large-scale gene expression data set. The subsequent inclusion of this information during data analysis and visualization allows for deeper insight into gene expression patterns. The set of DRAGON View tools provides methods for the analysis and visualization of expression patterns in relation to annotated information. Instead of incorporating the standard set of clustering and graphing tools available in many large-scale expression data analysis software packages, DRAGON View has been specifically designed to allow for the analysis of expression data in relation to the biological characteristics of gene sets.