UNIT 7.6 Integrating Whole-Genome Expression Results into Metabolic Networks with Pathway Processor
Published Online: 1 MAY 2004
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Bioinformatics
How to Cite
Cavalieri, D. and Grosu, P. 2004. Integrating Whole-Genome Expression Results into Metabolic Networks with Pathway Processor. Current Protocols in Bioinformatics. 5:7.6:7.6.1–7.6.19.
- Published Online: 1 MAY 2004
- Published Print: MAR 2004
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Genes never act alone in a biological system, but participate in a cascade of networks. As a result, analyzing microarray data from a pathway perspective leads to a new level of understanding the system. The authors' group has recently developed Pathway Processor (http://cgr.harvard.edu/cavalieri/pp.html), an automatic statistical method to determine which pathways are most affected by transcriptional changes and to map expression data from multiple whole-genome expression experiments on metabolic pathways. This unit presents applications of the Pathway Processor software.