UNIT 8.2 Prediction of Protein-Protein Interaction Networks
Published Online: 1 JUN 2008
Copyright © 2008 by John Wiley & Sons, Inc.
Lab Protocol Title
Current Protocols in Bioinformatics
How to Cite
Gomez, S. M., Choi, K. and Wu, Y. 2008. Prediction of Protein-Protein Interaction Networks. Current Protocols in Bioinformatics. 22:8.2:8.2.1–8.2.14.
- Published Online: 1 JUN 2008
- Published Print: JUN 2008
This unit offers a general overview of several techniques that have been developed for inferring functional and/or protein-protein interaction networks. The majority of these use whole-genome sequences as their primary input source of data. In addition, a few methods that utilize both protein features and experimental protein-protein interaction data directly in the prediction of new interactions have recently been developed. While an exhaustive list of approaches is not presented, it is hoped that the reader will gain a sense of how these approaches are implemented and an idea of their relative strengths and weaknesses, and a broader perspective on the type of work being conducted in this highly active area of research. Curr. Protoc. Bioinform. 22:8.2.1–8.2.14. © 2008 by John Wiley & Sons, Inc.
- protein interactions;
- interaction networks