UNIT 8.8 Analyzing Networks with VisANT

  1. Zhenjun Hu,
  2. Joseph Mellor,
  3. Charles DeLisi

Published Online: 1 DEC 2004

DOI: 10.1002/0471250953.bi0808s08

Current Protocols in Bioinformatics

Current Protocols in Bioinformatics

How to Cite

Hu, Z., Mellor, J. and DeLisi, C. 2004. Analyzing Networks with VisANT. Current Protocols in Bioinformatics. 8:8.8:8.8.1–8.8.24.

Author Information

  1. Boston University, Boston, Massachusetts

Publication History

  1. Published Online: 1 DEC 2004
  2. Published Print: NOV 2004

This is not the most recent version of the article. View current version (21 MAR 2014)


The VisANT tool, accessible from any recent Java-enabled browser, is a platform-independent, flexible, Web-enabled program for quick and simple construction, visualization, and analysis of molecular and higher order networks based on functional (e.g., expression profiles, phylogenetic profiles) and physical (e.g., yeast two-hybrid, chromatin-immunoprecipitation) relations from either the Predictome database or user-defined data sets. Analysis capabilities include identification of feed-forward and -back loops, shortest paths, and node degree distribution. Additionally, network constructs can be saved, accessed, and shared online. VisANT is able to develop and display meta-networks for meta-nodes that are structural complexes or pathways (soon including nodes representing any kind of dense cluster). Further, VisANT supports a growing number of standard exchange formats and database referencing standards, e.g., KEGG/KGML, BioPAX (in progress), GenBank, Gene Ontology. Multiple species are supported to the extent that computed or experimental evidence of interactions or associations are available (i.e., public datasets or Predictome database).


  • interaction;
  • network;
  • meta-network;
  • visualization;
  • integration