Unit

UNIT 9.9 Using the Generic Genome Browser (GBrowse)

  1. Maureen J. Donlin

Published Online: 1 DEC 2009

DOI: 10.1002/0471250953.bi0909s28

Current Protocols in Bioinformatics

Current Protocols in Bioinformatics

How to Cite

Donlin, M. J. 2009. Using the Generic Genome Browser (GBrowse). Current Protocols in Bioinformatics. 28:9.9:9.9.1–9.9.25.

Author Information

  1. Department of Biochemistry and Molecular Biology and Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri

Publication History

  1. Published Online: 1 DEC 2009
  2. Published Print: DEC 2009

Abstract

A genome browser is software that allows users to visualize DNA, protein, or other sequence features within the context of a reference sequence, such as a chromosome or contig. The Generic Genome Browser (GBrowse) is an open-source browser developed as part of the Generic Model Organism Database project (Stein et al., 2002). GBrowse can be configured to display genomic sequence features for any organism and is the browser used for the model organisms Drosophila melanogaster (Grumbling and Strelets, 2006) and Caenorhabditis elegans (Schwarz et al., 2006), among others. The software package can be downloaded from the Web and run on a Windows, Mac OS X, or Unix-type system. Version 1.64, as described in the original protocol, was released in November 2005, but the software is under active development and new versions are released about every six months. This update includes instructions on updating existing data sources with new files from NCBI. Curr. Protoc. Bioinform. 28:9.9.1-9.9.25. © 2009 by John Wiley & Sons, Inc.

Keywords:

  • computational biology;
  • genome;
  • GBrowse;
  • genome browser