UNIT 10.1 Introduction to Comparing Large Sequence Sets
Published Online: 1 FEB 2003
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Bioinformatics
How to Cite
Page, R. D. 2003. Introduction to Comparing Large Sequence Sets. Current Protocols in Bioinformatics. 00:10.1:10.1.1–10.1.2.
- Published Online: 1 FEB 2003
- Published Print: JAN 2003
Comparisons of whole genomes can yield important insights into the evolution of genome structure, such as the role of inversions in bacterial evolution and the identification of large-scale duplications in the human genome. This unit briefly compares two tools for aligning whole genome sequences: MUMmer and PipMaker. These tools differ in both the underlying algorithms used, and in the interface they present to the user.