Unit

UNIT 10.1 Introduction to Comparing Large Sequence Sets

  1. Roderic D.M. Page

Published Online: 1 FEB 2003

DOI: 10.1002/0471250953.bi1001s00

Current Protocols in Bioinformatics

Current Protocols in Bioinformatics

How to Cite

Page, R. D. 2003. Introduction to Comparing Large Sequence Sets. Current Protocols in Bioinformatics. 00:10.1:10.1.1–10.1.2.

Author Information

  1. University of Glasgow, Glasgow, Scotland

Publication History

  1. Published Online: 1 FEB 2003
  2. Published Print: JAN 2003

Abstract

Comparisons of whole genomes can yield important insights into the evolution of genome structure, such as the role of inversions in bacterial evolution and the identification of large-scale duplications in the human genome. This unit briefly compares two tools for aligning whole genome sequences: MUMmer and PipMaker. These tools differ in both the underlying algorithms used, and in the interface they present to the user.