UNIT 11.1 An Introduction to the Informatics of “Next-Generation” Sequencing
Published Online: 1 DEC 2011
Copyright © 2011 by John Wiley & Sons, Inc.
Lab Protocol Title
Current Protocols in Bioinformatics
How to Cite
Stein, L. D. 2011. An Introduction to the Informatics of “Next-Generation” Sequencing. Current Protocols in Bioinformatics. 36:11.1.1–11.1.9.
- Published Online: 1 DEC 2011
- Published Print: DEC 2011
Next-generation sequencing (NGS) packs the sequencing throughput of a 2000's-era genome center into a single affordable machine. However, software developed for conventional sequencing technologies is often inadequate to deal with the nature of NGS technologies, which produce short, massively parallel reads. This unit surveys the software packages that are available for managing and analyzing NGS data. Curr. Protoc. Bioinform. 36:11.1.1-11.1.9. © 2011 by John Wiley & Sons, Inc.
Keywords: next generation; genome; sequencing; bioinformatics; analysis