Unit

UNIT 11.13 Efficient Alignment of Illumina-Like High-Throughput Sequencing Reads with the GEnomic Multi-tool (GEM) Mapper

  1. Santiago Marco-Sola1,
  2. Paolo Ribeca1,2

Published Online: 19 JUN 2015

DOI: 10.1002/0471250953.bi1113s50

Current Protocols in Bioinformatics

Current Protocols in Bioinformatics

How to Cite

Marco-Sola, S. and Ribeca, P. 2015. Efficient alignment of illumina-like high-throughput sequencing reads with the GEnomic Multi-tool (GEM) mapper. Curr. Protoc. Bioinform. 50:11.13.1-11.13.20. doi: 10.1002/0471250953.bi1113s50

Author Information

  1. 1

    Centro Nacional de Análisis Genómico, Barcelona, Spain

  2. 2

    The Pirbright Institute, Woking, United Kingdom

Publication History

  1. Published Online: 19 JUN 2015

Abstract

Modern Illumina-like high-throughput sequencing machines allow the cheap decoding of great amounts of DNA. The GEnomic Multi-tool (GEM) mapper is one of the fastest and most sensitive methods known to date to align such data to a known genomic reference. This unit explains how to use it effectively. © 2015 by John Wiley & Sons, Inc.

Keywords:

  • sequencing;
  • high-throughput sequencing;
  • next-generation sequencing;
  • bioinformatics;
  • genomics;
  • alignment;
  • mapping;
  • read mapping;
  • sequencing read mapping