UNIT 13.15 Biological Sequence Motif Discovery Using motif-x
Published Online: 1 SEP 2011
Copyright © 2011 by John Wiley & Sons, Inc.
Lab Protocol Title
Current Protocols in Bioinformatics
How to Cite
Chou, M. F. and Schwartz, D. 2011. Biological Sequence Motif Discovery Using motif-x. Current Protocols in Bioinformatics. 35:13.15:13.15.1–13.15.24.
- Published Online: 1 SEP 2011
- Published Print: SEP 2011
The Web-based motif-x program provides a simple interface to extract statistically significant motifs from large data sets, such as MS/MS post-translational modification data and groups of proteins that share a common biological function. Users upload data files and download results using common Web browsers on essentially any Web-compatible computer. Once submitted, data analyses are performed rapidly on an associated high-speed computer cluster and they produce both syntactic and image-based motif results and statistics. The protocols presented demonstrate the use of motif-x in three common user scenarios. Curr. Protoc. Bioinform. 35:13.15.1-13.15.24. © 2011 by John Wiley & Sons, Inc.
- protein motif;
- post-translational modification (PTM);
- motif discovery;
- mass spectrometry;