Unit
UNIT 13.16 Using the scan-x Web Site to Predict Protein Post-Translational Modifications
Published Online: 1 DEC 2011
DOI: 10.1002/0471250953.bi1316s36
Copyright © 2011 by John Wiley & Sons, Inc.
Lab Protocol Title
Current Protocols in Bioinformatics
Additional Information
How to Cite
Chou, M. F. and Schwartz, D. 2011. Using the scan-x Web Site to Predict Protein Post-Translational Modifications. Current Protocols in Bioinformatics. 36:13.16:13.16.1–13.16.8.
Publication History
- Published Online: 1 DEC 2011
- Published Print: DEC 2011
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Abstract
The recent plethora of proteomic mass spectrometry data is providing evidence that almost every protein in the cell undergoes some form of post-translational modification. We describe a protocol to use the scan-x Web site to view predicted acetylation sites in the human proteome and predicted phosphorylation sites in the human, mouse, fly, and yeast proteomes with high specificity. This tool is accessible from virtually any computer with a Web browser. The only requirement is a means of searching for a protein of interest in one of the represented organisms. Curr. Protoc. Bioinform. 36:13.16.1-13.16.8. © 2011 by John Wiley & Sons, Inc.
Keywords:
- acetylation;
- phosphorylation;
- post-translational modification (PTM);
- scan-x;
- motif-x;
- mass spectrometry;
- proteomics
