Unit

UNIT 14.2 Using Pharmabase to Perform Pharmacological Analyses of Cell Function

  1. Peter J. S. Smith,
  2. David Remsen

Published Online: 1 MAR 2006

DOI: 10.1002/0471250953.bi1402s13

Current Protocols in Bioinformatics

Current Protocols in Bioinformatics

How to Cite

Smith, P. J. S. and Remsen, D. 2006. Using Pharmabase to Perform Pharmacological Analyses of Cell Function. Current Protocols in Bioinformatics. 13:14.2:14.2.1–14.2.17.

Author Information

  1. BioCurrents Research Center, Marine Biological Laboratory, Woods Hole, Massachusetts

Publication History

  1. Published Online: 1 MAR 2006
  2. Published Print: FEB 2006

Abstract

Pharmabase is designed to form a bridge between the molecular dimension of cell transport processes and the functional manipulation of the protein players. It has as its emphasis membrane transport and related pharmacology. Several search and navigation options are available, including membrane transport, disease, and a graphic interface arranged by pathway and cell type. The level of entry to the database can be tailored to the investigator's level of expertise. The final product of Pharmabase is a Compound Record detailing the use and targets of individual compounds. Navigation routes generally fall into hierarchical keys and are cross-referenced. Pharmabase encourages input from its user community. It is maintained by the BioCurrents Research Center, an NIH resource funded through the National Center for Research Resources (NCRR).

Keywords:

  • Pharmacology;
  • Channels;
  • Pumps;
  • Carriers;
  • Protein transporters