Unit

UNIT 14.5 Using ChemBank to Probe Chemical Biology

  1. Kathleen Petri Seiler,
  2. Heidi Kuehn,
  3. Mary Pat Happ,
  4. Dave DeCaprio,
  5. Paul A. Clemons

Published Online: 1 JUN 2008

DOI: 10.1002/0471250953.bi1405s22

Current Protocols in Bioinformatics

Current Protocols in Bioinformatics

How to Cite

Petri Seiler, K., Kuehn, H., Pat Happ, M., DeCaprio, D. and Clemons, P. A. 2008. Using ChemBank to Probe Chemical Biology. Current Protocols in Bioinformatics. 22:14.5:14.5.1–14.5.26.

Author Information

  1. Chemical Biology Program and Platform, Broad Institute of Harvard and MIT, Cambridge, Massachusetts

Publication History

  1. Published Online: 1 JUN 2008
  2. Published Print: JUN 2008

Abstract

ChemBank (http://chembank.broad.harvard.edu/) is a public, Web-based informatics environment. ChemBank stores and makes freely available data derived from small molecules and small-molecule screens and has resources for relating and studying these data. Currently, ChemBank stores information on hundreds of thousands of small molecules and hundreds of biomedically relevant assays performed at the Broad Institute screening center. Web-based analysis tools are available within ChemBank to study the relationships between small molecules, cell measurements, and cell states. This unit demonstrates the use of ChemBank data to ask and answer questions relating to chemical biology and screening experiments contained within ChemBank. Curr. Protoc. Bioinform. 22:14.5.1–14.5.26. © 2008 by John Wiley & Sons, Inc.

Keywords:

  • chemical biology;
  • cheminformatics;
  • data analysis;
  • database;
  • high-throughput screening;
  • small molecule