UNIT 15.5 Using SomaticSniper to Detect Somatic Single Nucleotide Variants
Published Online: 21 MAR 2014
Copyright © 2013 John Wiley & Sons, Inc. All rights reserved.
Lab Protocol Title
Current Protocols in Bioinformatics
How to Cite
Larson, D. E., Abbott, T. E. and Wilson, R. K. 2014. Using SomaticSniper to Detect Somatic Single Nucleotide Variants. Current Protocols in Bioinformatics. 15:15.5:15.5.1–15.5.8.
- Published Online: 21 MAR 2014
Detecting somatic single nucleotide variants (SNVs) is an essential component of cancer research with next-generation sequencing data. This unit describes how to run the SomaticSniper somatic SNV detector and then filter the output to eliminate most false positives. It also includes support protocols detailing the compilation of the software. Curr. Protoc. Bioinform. 45:15.5.1-15.5.8. © 2014 by John Wiley & Sons, Inc.
- next-generation sequencing;
- somatic variant calling;