The Diels-Alder Reaction with Maleic Anhydride
Published Online: 15 MAR 2011
Copyright © 2004 by Organic Reactions, Inc. Published by John Wiley & Sons, Inc.
How to Cite
Kloetzel, M. C. 2011. The Diels-Alder Reaction with Maleic Anhydride . Organic Reactions. 4:1:1–59.
- Published Online: 15 MAR 2011
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The Diels-Alder reaction consists in an addition of a compound containing a double or triple bond (usually activated by additional unsaturation in the alpha, beta-position) to the 1,4-positions of a conjugated dienes system with the formation of a six-membered ring, Various dienes systems to dienophiles are described as typical examples of the Diels-Alder reaction. A noteworthy feature of this reaction is the great variety of compounds that may serve as the dienophile. Among the most widely employed dienophiles are maleic anhydride and closely related dicarboxylic acid derivatives.
- Diels-Alder reaction;
- malic anhydride;
- acyclic compounds;
- aromatic compounds;
- heterocyclic compounds;
- diene analysis;
- side reactions;
- experimental procedures