The Synthesis of Aliphatic and Alicyclic Nitro Compounds†
Published Online: 15 MAR 2011
Copyright © 2004 by Organic Reactions, Inc. Published by John Wiley & Sons, Inc.
How to Cite
Kornblum, N. 2011. The Synthesis of Aliphatic and Alicyclic Nitro Compounds. Organic Reactions. 12:3:101–156.
- Published Online: 15 MAR 2011
Choose one or more boxes to highlight terms.
This chapter is concerned with the synthesis of nitro compounds in which the nitro group is on a saturated carbon atom. The most important methods available are as follows: 1. Treatment of alkyl halides with silver nitrite; 2. Reaction of allyl bromides and iodides with sodium nitrite; 3. Oxidation of amines; 4. Oxidation of oximes; 5. Nitration of active methylene compounds; 6, Nitration of active methylene compounds with nitric acid. These reactions are discussed and also noted are miscellaneous reactions of limited utility. Comparison of methods is given.
- aliphatic nitro compounds;
- alicyclic nitro compounds;
- silver nitrite;
- sodium nitrite;
- active methylene compounds;
- nitric acid;
- nitro group