Chapter 5. Copper Enzymes

  1. Rosette M. Roat-Malone

Published Online: 19 MAR 2003

DOI: 10.1002/0471265330.ch5

Bioinorganic Chemistry: A Short Course

Bioinorganic Chemistry: A Short Course

How to Cite

Roat-Malone, R. M. (2002) Copper Enzymes, in Bioinorganic Chemistry: A Short Course, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471265330.ch5

Author Information

  1. Washington College, Chestertown, MD, USA

Publication History

  1. Published Online: 19 MAR 2003
  2. Published Print: 20 SEP 2002

ISBN Information

Print ISBN: 9780471159766

Online ISBN: 9780471265337



  • copper enzymes;
  • occurrence;
  • structure;
  • function;
  • specific enzymes;
  • model compounds;
  • hemocyanin;
  • azurin


A diverse variety of copper-containing metalloenzymes occur in plants and animals. We present a detailed discussion of several of these copper enzymes, and copper proteins such as the blue copper electron transfer proteins stellacyanin, amicyanin, auracyanin, and rusticyanin. Also, electron structure and molecular orbital theory for blue copper proteins in relation to electron transfer pathways are discussed. Spectral properties and their relation to geometry for trinuclear copper cluster sites, such as found in laccase, are described as well.