Standard Article

Dynamic Transmission Electron Microscopy

Electron Techniques

  1. James E. Evans1,
  2. Katherine L. Jungjohann2,
  3. Nigel D. Browning3

Published Online: 12 OCT 2012

DOI: 10.1002/0471266965.com158

Characterization of Materials

Characterization of Materials

How to Cite

Evans, J. E., Jungjohann, K. L. and Browning, N. D. 2012. Dynamic Transmission Electron Microscopy. Characterization of Materials. 1–15.

Author Information

  1. 1

    Environmental Molecular Sciences Laboratory, Richland, WA, USA

  2. 2

    Department of Chemical Engineering and Materials Science, University of California Davis, Davis, CA, USA

  3. 3

    Fundamental and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA, USA

Publication History

  1. Published Online: 12 OCT 2012


Dynamic transmission electron microscopy (DTEM) combines the benefits of high spatial resolution electron microscopy with the high temporal resolution of ultrafast lasers. The incorporation of these two components into a single instrument provides a perfect platform for in situ observations of material processes. However, previous applications for the first-generation DTEM have focused primarily on observing structural changes occurring in samples exposed to high vacuum and have demonstrated a spatial resolution of 8 nm with a combined 15 ns temporal resolution. Yet, improved spatial resolution will be necessary for understanding dynamics of individual particles rather than bulk materials or thin films. Therefore, in order to expand the pump–probe experimental regime to more natural environmental conditions, in situ gas and liquid chambers must be coupled with a second-generation aberration-corrected DTEM that has been modeled to achieve better than 0.3 nm spatial resolution with 1 μs temporal resolution. This chapter describes the current and future applications of in situ liquid DTEM to permit time-resolved atomic scale observations in an aqueous environment. Although this chapter focuses mostly on in situ liquid imaging, the same research potential exists for in situ gas experiments and the successful integration of these techniques promises new insights for understanding nanoparticle, catalyst, and biological protein dynamics with unprecedented spatiotemporal resolution.


  • In situ TEM;
  • DTEM;
  • ultrafast electron microscopy