Chapter 4. Reversible Enzyme Inhibition
- Alejandro G. Marangoni
Published Online: 13 MAR 2003
Copyright © 2003 John Wiley & Sons, Inc.
Enzyme Kinetics: A Modern Approach
How to Cite
Marangoni, A. G. (2003) Reversible Enzyme Inhibition, in Enzyme Kinetics: A Modern Approach (ed A. G. Marangoni), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471267295.ch4
Department of Food Science, University of Guelph, Canada
- Published Online: 13 MAR 2003
- Published Print: 1 NOV 2002
Print ISBN: 9780471159858
Online ISBN: 9780471267294
- reversible inhibition;
- linear mixed-type
This chapter reviews the four basic types of reversible enzyme inhibition, namely competitive, uncompetitive, non-competitive and linear mixed-type. Equilibrium kinetic models are derived from first principles. Examples of the analysis of inhibition kinetic data for the determination of the inhibition constant, Ki, are presented. All analyses are exclusively carried out using non-linear regression techniques.