Chapter 5. Irreversible Enzyme Inhibition
- Alejandro G. Marangoni
Published Online: 13 MAR 2003
DOI: 10.1002/0471267295.ch5
Copyright © 2003 John Wiley & Sons, Inc.
Book Title
Enzyme Kinetics: A Modern Approach
Additional Information
How to Cite
Marangoni, A. G. (2003) Irreversible Enzyme Inhibition, in Enzyme Kinetics: A Modern Approach (ed A. G. Marangoni), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471267295.ch5
Editor Information
Department of Food Science, University of Guelph, Canada
Publication History
- Published Online: 13 MAR 2003
- Published Print: 1 NOV 2002
ISBN Information
Print ISBN: 9780471159858
Online ISBN: 9780471267294
- Summary
- Chapter
Keywords:
- irreversible inhibition;
- Ki;
- simple;
- time-dependent
Summary
In this chapter, models for irreversible inhibition are derived from first principles for simple and time-dependent irreversible enzyme inhibition in the presence and absence of substrate. Differentiation between simple and time-dependent irreversible inhibition is also discussed.