Chapter 1. Families of Transporters and Their Classification

  1. Michael W. Quick Ph.D.
  1. Milton H. Saier Jr.

Published Online: 19 MAR 2003

DOI: 10.1002/0471434043.ch1

Transmembrane Transporters

Transmembrane Transporters

How to Cite

Saier, M. H. (2002) Families of Transporters and Their Classification, in Transmembrane Transporters (ed M. W. Quick), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471434043.ch1

Editor Information

  1. Department of Neurobiology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA

Author Information

  1. Department of Biology, University of California at San Diego, La Jolla, CA, USA

Publication History

  1. Published Online: 19 MAR 2003
  2. Published Print: 23 AUG 2002

Book Series:

  1. Receptor Biochemistry and Methodology

Book Series Editors:

  1. David R. Sibley

Series Editor Information

  1. Molecular Neuropharmacology Section, Experimental Therapeutics Branch, NINDS, National Institutes of Health, Bethesda, Maryland, USA

ISBN Information

Print ISBN: 9780471065135

Online ISBN: 9780471434047



  • transport proteins;
  • phylogeny;
  • classification;
  • biosystematics;
  • evolution


Thirty completely sequenced genomes of bacteria, archaea and eukaryotes have been surveyed for the presence of genes encoding homologues of known solute transport proteins. These analyses and others have revealed the presence of over 350 families of sequence-related transporters. All such proteins have been classified according to a system that we call the transporter classification (TC) system. In this short summary chapter, the main features of this system are described, and the families are presented.