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“Click” Chemistry in Macromolecular Synthesis

  1. Wolfgang H. Binder,
  2. Ronald Zirbs

Published Online: 16 MAR 2009

DOI: 10.1002/0471440264.pst565

Encyclopedia of Polymer Science and Technology

Encyclopedia of Polymer Science and Technology

How to Cite

Binder, W. H. and Zirbs, R. 2009. “Click” Chemistry in Macromolecular Synthesis. Encyclopedia of Polymer Science and Technology. .

Author Information

  1. Martin-Luther University Halle-Wittenberg, Halle (Saale), Germany

Publication History

  1. Published Online: 16 MAR 2009

Abstract

“Click” chemistry is a valuable tool in polymer science for the efficient linkage of functional entities, oligomers or polymers, yielding access to functional homo-, block-, star-, graft-polymers as well as higher polymeric architectures (dendrimers, hyperbranched polymers, supramolecular polymers, gels, polymer brushes). Besides other efficient “click” reactions, the copper-(I)-catalyzed 1,3-dipolar-azide/alkyne cycloaddition reaction has emerged as the method of choice to this and related purposes. Main advantage in relation to conventional linking reactions are (1) quantitative yields, (2) mild reaction conditions, (3) solvent and substrate insensitivity, and (4) high yielding reactions under both homogeneous and heterogeneous reaction conditions. The article describes basics of the reaction as well as applications in polymer science and technology.

Keywords:

  • azide-alkyne “click”;
  • biopolymers;
  • 1,3-dipolar cycloaddition;
  • reaction;
  • polymers;
  • surfaces