Basic Local Alignment Search Tool (BLAST)

  1. Jonathan Pevsner

Published Online: 28 JAN 2005

DOI: 10.1002/047145916X.ch4

Bioinformatics and Functional Genomics

Bioinformatics and Functional Genomics

How to Cite

Pevsner, J. (2005) Basic Local Alignment Search Tool (BLAST), in Bioinformatics and Functional Genomics, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/047145916X.ch4

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 18 JUN 2004

ISBN Information

Print ISBN: 9780471210047

Online ISBN: 9780471459163

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Keywords:

  • basic local alignment search tool;
  • nucleotide sequences;
  • computer algorithms;
  • sequence databases;
  • formatting parameter searching

Summary

This chapter includes the following topics:

  • Introduction

  • BLAST Search Steps

  • BLAST Algorithm Uses Local Alignment Search Strategy

  • BLAST Search Strategies

  • BLAST Searching with Multidomain Protein: HIV-1 pol

  • BLAST Searching with Lipocalins: Effect of Changing Scoring Matrices

  • Perspective

  • Pitfalls

  • Web Resources

  • Discussion Questions

  • Problems

  • Self-Test Quiz

  • Suggested Reading