Chapter 4. DNA Structure and the Genetic Code

  1. Stephen R. Bolsover1,
  2. Jeremy S. Hyams2,
  3. Elizabeth A. Shephard3,
  4. Hugh A. White3,
  5. Claudia G. Wiedemann1

Published Online: 27 JAN 2004

DOI: 10.1002/047146158X.ch4

Cell Biology: A Short Course, Second Edition

Cell Biology: A Short Course, Second Edition

How to Cite

Bolsover, S. R., Hyams, J. S., Shephard, E. A., White, H. A. and Wiedemann, C. G. (2004) DNA Structure and the Genetic Code, in Cell Biology: A Short Course, Second Edition, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/047146158X.ch4

Author Information

  1. 1

    Department of Physiology, University College, London, UK

  2. 2

    Department of Biology, University College, London, UK

  3. 3

    Department of Biochemistry and Molecular Biology, University College, London, UK

Publication History

  1. Published Online: 27 JAN 2004
  2. Published Print: 14 NOV 2003

ISBN Information

Print ISBN: 9780471263937

Online ISBN: 9780471461586

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Keywords:

  • DNA;
  • chromosome;
  • gene;
  • double helix;
  • plasmid;
  • genetic code;
  • reading frame;
  • mutation

Summary

In this chapter we describe the structure of DNA and introduce the concept of the gene. DNA forms a double helix and is packaged into chromosomes. Plasmids and viruses generally have small genomes, which are replicated in the infected host cell. We describe the genetic code, with its start and stop signals, introduce types of mutation, and illustrate these with the example of trimethylaminuria (fish odor syndrome).