6. Transcription and the Control of Gene Expression

  1. Stephen R. Bolsover1,
  2. Jeremy S. Hyams2,
  3. Elizabeth A. Shephard3,
  4. Hugh A. White3 and
  5. Claudia G. Wiedemann1

Published Online: 27 JAN 2004

DOI: 10.1002/047146158X.ch6

Cell Biology: A Short Course, Second Edition

Cell Biology: A Short Course, Second Edition

How to Cite

Bolsover, S. R., Hyams, J. S., Shephard, E. A., White, H. A. and Wiedemann, C. G. (2003) Transcription and the Control of Gene Expression, in Cell Biology: A Short Course, Second Edition, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/047146158X.ch6

Author Information

  1. 1

    Department of Physiology, University College, London, UK

  2. 2

    Department of Biology, University College, London, UK

  3. 3

    Department of Biochemistry and Molecular Biology, University College, London, UK

Publication History

  1. Published Online: 27 JAN 2004
  2. Published Print: 14 NOV 2003

ISBN Information

Print ISBN: 9780471263937

Online ISBN: 9780471461586

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Keywords:

  • RNA;
  • promoter;
  • RNA polymerase;
  • operon;
  • TATA box;
  • alternative splicing;
  • transcription factor

Summary

In this chapter we describe the structure of RNA and how RNA is synthesized on the DNA template. We describe bacterial operons and the control of their expression, then the more complex process of RNA synthesis in eukaryotes. We introduce enhancer sequences and transcription factors, using the example of the glucocorticoid receptor.