5. Chiral Molecular Self-Assembly

  1. Mark M. Green2,
  2. R. J. M. Nolte3 and
  3. E. W. Meijer4
  1. Mark S. Spector,
  2. Jonathan V. Selinger and
  3. Joel M. Schnur

Published Online: 14 MAY 2004

DOI: 10.1002/0471471895.ch5

Materials-Chirality, Volume 24

Materials-Chirality, Volume 24

How to Cite

Spector, M. S., Selinger, J. V. and Schnur, J. M. (2003) Chiral Molecular Self-Assembly, in Materials-Chirality, Volume 24 (eds M. M. Green, R. J. M. Nolte and E. W. Meijer), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471471895.ch5

Editor Information

  1. 2

    Polytechnic University, Brooklyn, New York, USA

  2. 3

    Laboratory of Organic Chemistry, Department of Organic Chemistry, NSRIM, University of Nijmegen, Toernooiveld 1, 6525 ED, Nijmegen, The Netherlands

  3. 4

    Laboratory of Macromolecular and Organic Chemistry, Eindhoven University of Technology, P.O. Box 513, 5600 MB, Eindhoven, The Netherlands

Author Information

  1. Naval Research Laboratory, Center for Bio/Molecular Science and Engineering, 4555 Overlook Avenue SW, Washington, D.C. 20375-5348

Publication History

  1. Published Online: 14 MAY 2004
  2. Published Print: 25 SEP 2003

Book Series:

  1. Topics in Stereochemistry

Book Series Editors:

  1. Scott E. Denmark and
  2. Jay Siegel

ISBN Information

Print ISBN: 9780471054979

Online ISBN: 9780471471899



  • carbohydrate amphiphiles;
  • aldonamides;
  • glycolipids;
  • cerebrosides;
  • peptide-based amphiphiles;
  • amino acid amphiphiles;
  • peptides;
  • phospholipids;
  • diacetylenic phospholipids;
  • diacetylenic phosphonate lipids;
  • phospholipid mixtures;
  • related chiral systems;
  • nucluotides;
  • steroid-based systems;
  • gemini surfactants;
  • models of chiral self-assembly;
  • nonchiral models – electrostatics – elasticity of orientational order – spontaneous curvature;
  • chiral models: molecular approach;
  • continuum elastic theory: membranes with uniform tilt direction;
  • membranes with variations in tilt direction;
  • cylindrical versus Gaussian curvature;
  • chiral symmetry-breaking;
  • biased chiral symmetry-breaking


The unique features of the chiral self-assembly of small molecules are described. In particular, the hierarchy in the formation from isolated molecule to mesoscopic ordering to macroscopic ordering is elucidated. Many recent examples are reviewed