SNPs and Functional Polymorphisms in Cancer

  1. Charles Brenner and
  2. David Duggan
  1. Penelope E. Bonnen and
  2. David L. Nelson

Published Online: 28 JAN 2005

DOI: 10.1002/047147665X.ch4

Oncogenomics: Molecular Approaches to Cancer

Oncogenomics: Molecular Approaches to Cancer

How to Cite

Bonnen, P. E. and Nelson, D. L. (2004) SNPs and Functional Polymorphisms in Cancer, in Oncogenomics: Molecular Approaches to Cancer (eds C. Brenner and D. Duggan), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/047147665X.ch4

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 15 MAR 2004

ISBN Information

Print ISBN: 9780471225928

Online ISBN: 9780471476658

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Keywords:

  • functional polymorphisms;
  • SNPs;
  • haplotypes;
  • linkage disequilibrium

Summary

This chapter includes the following topics:

  • Introduction

  • Strategy for Discovery of Functional Polymorphisms

  • The Utility of SNPs

  • Haplotypes: Leveraging up Study Power

  • The Importance of Characterizing LD and Haplotype Diversity

  • Confirming Associations and Functional Polymorphisms

  • Summary and Perspectives