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Histopathology in Biomonitoring Marine Invertebrates


  1. M.L. Martín-Díaz1,2,
  2. N. Jiménez-Tenorio3,
  3. C. Sarasquete1,2,
  4. M.L. González de Canales3,
  5. T.A. DelValls2,3

Published Online: 15 JUL 2005

DOI: 10.1002/047147844X.oc61

Water Encyclopedia

Water Encyclopedia

How to Cite

Martín-Díaz, M., Jiménez-Tenorio, N., Sarasquete, C., González de Canales, M. and DelValls, T. 2005. Histopathology in Biomonitoring Marine Invertebrates. Water Encyclopedia. 4.

Author Information

  1. 1

    Instituto de Ciencias Marinas de Andalucía (ICMAN), Consejo Superior de Investigaciones Científicas (CSIC), Cádiz, Spain

  2. 2

    Unidad Asociada (UCA&CSIC) (CAPA), Cádiz, Spain

  3. 3

    Universidad de Cádiz, Cádiz, Spain

Publication History

  1. Published Online: 15 JUL 2005


The use of the histopathological alterations as a biomarker of effect in marine invertebrates has been widely included in the assessment of the quality of the marine environment. This biomarker may link the bioavailability of different compounds with the effect at target tissues and it has been successfully included in major national monitoring programmes. Nevertheless, this biomarker is still under a experimental stage.

The present work critically reviews the advantages and limitations of the use of this biomarker: the methodology for its determination and its inclusion as a complementary tool for the marine pollution assessment in a Weight of Evidence (WOE) approach.


  • biomarkers;
  • toxicity;
  • weight of evidence;
  • invertebrate diseases