Chapter 15. Mass Spectrometry of Biomolecules

  1. Susan R. Mikkelsen1,
  2. Eduardo Cortón2

Published Online: 26 FEB 2004

DOI: 10.1002/0471623628.ch15

Book Title

Bioanalytical Chemistry

Bioanalytical Chemistry

Additional Information

How to Cite

Mikkelsen, S. R. and Cortón, E. (2004) Mass Spectrometry of Biomolecules, in Bioanalytical Chemistry, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471623628.ch15

Author Information

  1. 1

    University of Waterloo, Ontario, Canada

  2. 2

    University of Buenos Aires, Argentina

Publication History

  1. Published Online: 26 FEB 2004
  2. Published Print: 20 FEB 2004

ISBN Information

Print ISBN: 9780471544470

Online ISBN: 9780471623625

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Keywords:

  • mass spectrometry;
  • instrumentation;
  • soft ionization sources;
  • mass analyzers;
  • detectors;
  • interpretation of mass spectra;
  • molecular weight determination;
  • protein identification;
  • sequencing;
  • nucleic acids;
  • bacterial mass spectrometry

Summary

Mass spectrometry of biomolecules, including a basic description of instrumentation, soft ionization sources, fast atom/ion bombardment (FAB), electrospray ionization (ESI), matrix-assisted laser desorption/ionization (MALDI), mass analyzers, detectors, interpretation of mass spectra, biomolecule molecular weight determination, protein identification, protein–peptide sequencing, nucleic acid applications, bacterial mass spectrometry.

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