15. Apoptosis Signaling in Normal and Cancer Cells

  1. Gary S. Stein Ph.D.2 and
  2. Arthur B. Pardee Ph.D.3
  1. Shulin Wang and
  2. Wafik S. El-Deiry

Published Online: 28 JAN 2005

DOI: 10.1002/0471656437.ch15

Cell Cycle and Growth Control: Biomolecular Regulation and Cancer, Second Edition

Cell Cycle and Growth Control: Biomolecular Regulation and Cancer, Second Edition

How to Cite

Wang, S. and El-Deiry, W. S. (2004) Apoptosis Signaling in Normal and Cancer Cells, in Cell Cycle and Growth Control: Biomolecular Regulation and Cancer, Second Edition (eds G. S. Stein and A. B. Pardee), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471656437.ch15

Editor Information

  1. 2

    Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts, USA

  2. 3

    Department of Biological Chemistry and Molecular Pharmacology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA

Author Information

  1. Howard Hughes Medical Institute, Departments of Medicine, Genetics, Pharmacology, and Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 10 MAY 2004

ISBN Information

Print ISBN: 9780471250715

Online ISBN: 9780471656432

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Keywords:

  • apoptosis signaling;
  • tumor-necrosis factor(TNF);
  • apoptosis cell death

Summary

This chapter contains sections titled:

  • Introduction

  • Major Mediators of Apoptosis

  • Apoptosis Signaling

  • Apoptosis and Normal Physiology

  • Apoptosis and Cancer

  • Apoptosis and Cancer Therapy

  • Conclusions and Perspective

  • Acknowledgments

  • References