18. Role of the Retinoblastoma Family in Cell Cycle Progression and Growth Control

  1. Gary S. Stein Ph.D.3 and
  2. Arthur B. Pardee Ph.D.4
  1. Valeria Masciullo1 and
  2. Antonio Giordano2

Published Online: 28 JAN 2005

DOI: 10.1002/0471656437.ch18

Cell Cycle and Growth Control: Biomolecular Regulation and Cancer, Second Edition

Cell Cycle and Growth Control: Biomolecular Regulation and Cancer, Second Edition

How to Cite

Masciullo, V. and Giordano, A. (2004) Role of the Retinoblastoma Family in Cell Cycle Progression and Growth Control, in Cell Cycle and Growth Control: Biomolecular Regulation and Cancer, Second Edition (eds G. S. Stein and A. B. Pardee), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471656437.ch18

Editor Information

  1. 3

    Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts, USA

  2. 4

    Department of Biological Chemistry and Molecular Pharmacology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA

Author Information

  1. 1

    Departments of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

  2. 2

    Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Temple University, Philadelphia, Pennsylvania, USA

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 10 MAY 2004

ISBN Information

Print ISBN: 9780471250715

Online ISBN: 9780471656432

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Keywords:

  • retinoblastoma gene family;
  • pocket proteins;
  • multiple genetic systems

Summary

This chapter contains sections titled:

  • Introduction

  • Growth Suppressive Properties

  • Rb Family and Development

  • Rb Family and Apoptosis

  • Rb Family and Differentiation

  • Rb Family and Angiogenesis

  • Deregulation of Rb Family Members in Cancer and Therapeutic Perspectives

  • Conclusions

  • Acknowledgments

  • References