21. Misregulated Fate—Cancer

  1. Gary S. Stein Ph.D.1 and
  2. Arthur B. Pardee Ph.D.2
  1. Arthur B. Pardee

Published Online: 28 JAN 2005

DOI: 10.1002/0471656437.ch21

Cell Cycle and Growth Control: Biomolecular Regulation and Cancer, Second Edition

Cell Cycle and Growth Control: Biomolecular Regulation and Cancer, Second Edition

How to Cite

Pardee, A. B. (2004) Misregulated Fate—Cancer, in Cell Cycle and Growth Control: Biomolecular Regulation and Cancer, Second Edition (eds G. S. Stein and A. B. Pardee), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471656437.ch21

Editor Information

  1. 1

    Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts, USA

  2. 2

    Department of Biological Chemistry and Molecular Pharmacology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA

Author Information

  1. Department of Biological Chemistry and Molecular Pharmacology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 10 MAY 2004

ISBN Information

Print ISBN: 9780471250715

Online ISBN: 9780471656432

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Keywords:

  • spectral karyotyping(SKY);
  • comparative genomic hybridization(CGH);
  • misregulated fate and molecular mechanisms

Summary

This chapter contains sections titled:

  • Cancer versus Normal Cells

  • Mutations in Cancer

  • General Themes of Dysregulation

  • Levels of Regulation

  • Quiescence versus Proliferation

  • Intracell Signaling

  • The Cell Cycle

  • Growth Termination

  • Cell Death

  • Mechanisms of Apoptosis

  • Stressed Cells

  • Developments in the Near Future