5. Organotin Oligomeric Drugs Containing the Antiviral Agent Acyclovir
- Alaa S. Abd-El-Aziz2,
- Charles E. Carraher Jr.3,
- Charles U. Pittman Jr.4,
- John E. Sheats5,
- Martel Zeldin6
Published Online: 28 JUL 2004
DOI: 10.1002/0471683779.ch5
Copyright © 2004 John Wiley & Sons, Inc.
Book Title
Macromolecules Containing Metal and Metal-Like Elements: Biomedical Applications, Volume 3
Additional Information
How to Cite
Carraher, C. E. and Bleicher, R. E. (2004) Organotin Oligomeric Drugs Containing the Antiviral Agent Acyclovir, in Macromolecules Containing Metal and Metal-Like Elements: Biomedical Applications, Volume 3 (eds A. S. Abd-El-Aziz, C. E. Carraher, C. U. Pittman, J. E. Sheats and M. Zeldin), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471683779.ch5
Editor Information
- 2
Department of Chemistry, The University of Winnipeg, Winnipeg, Manitoba, Canada
- 3
Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, Florida and Florida Center for Environmental Studies, Palm Beach Gardens, Florida, USA
- 4
Department of Chemistry, Mississippi State University, Mississippi State, Mississippi, USA
- 5
Department of Chemistry, Rider University, Lawrenceville, New Jersey, USA
- 6
Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York, USA
Publication History
- Published Online: 28 JUL 2004
- Published Print: 18 JUN 2004
ISBN Information
Print ISBN: 9780471667377
Online ISBN: 9780471683773
- Summary
- Chapter
Keywords:
- acyclovir;
- organotin;
- antiviral;
- mass spectrometry;
- polyorganotin ether amines;
- interfacial polymerization;
- interfacial polycondensation;
- bioactivity
Summary
The initial synthesis of organotin polymers containing the antiviral acyclovir is described. Structural analysis is described in some detail including mass spectrometry, molecular weight, and infrared analysis. The mechanism of polymer formation is discussed. The general activity of both acyclovir and organotin compounds is reviewed.