Chapter 3. Overview of Biological Mass Spectrometry

  1. Igor A. Kaltashov and
  2. Stephen J. Eyles

Published Online: 27 JAN 2005

DOI: 10.1002/0471705179.ch3

Mass Spectrometry in Biophysics: Conformation and Dynamics of Biomolecules

Mass Spectrometry in Biophysics: Conformation and Dynamics of Biomolecules

How to Cite

Kaltashov, I. A. and Eyles, S. J. (2005) Overview of Biological Mass Spectrometry, in Mass Spectrometry in Biophysics: Conformation and Dynamics of Biomolecules, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471705179.ch3

Author Information

  1. University of Massachusetts at Amherst, USA

Publication History

  1. Published Online: 27 JAN 2005
  2. Published Print: 6 APR 2005

Book Series:

  1. Wiley-Interscience Series in Mass Spectrometry

Book Series Editors:

  1. Dominic M. Desiderio2 and
  2. Nico M. M. Nibbering3

Series Editor Information

  1. 2

    Departments of Neurology and Biochemistry, University of Tennessee Health Science Center, USA

  2. 3

    Vrije Universiteit Amsterdam, The Netherlands

ISBN Information

Print ISBN: 9780471456025

Online ISBN: 9780471705178

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Keywords:

  • stable isotopes;
  • soft ionization;
  • electrospray ionization (ESI);
  • MALDI;
  • mass analyzers;
  • ion fragmentation;
  • tandem mass spectrometry;
  • LC-MS

Summary

The purpose of this chapter is to provide readers who are less familiar with mass spectrometry with concise background material on modern MS instrumentation and techniques that will be referred to in the later chapters. The idea is to equip the reader with a knowledge base that could later be used to make an informed choice as to the use of a particular instrument or technique for a specific task.