Chapter 3. The Genetic System: Mendel's Laws of Inheritance and Genetic Linkage

  1. Jack J. Pasternak

Published Online: 27 JAN 2005

DOI: 10.1002/0471719188.ch3

Book Title

An Introduction to Human Molecular Genetics: Mechanisms of Inherited Diseases, Second Edition

An Introduction to Human Molecular Genetics: Mechanisms of Inherited Diseases, Second Edition

Additional Information

How to Cite

Pasternak, J. J. (2005) The Genetic System: Mendel's Laws of Inheritance and Genetic Linkage, in An Introduction to Human Molecular Genetics: Mechanisms of Inherited Diseases, Second Edition, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471719188.ch3

Author Information

  1. University of Waterloo, Ontario, Canada

Publication History

  1. Published Online: 27 JAN 2005
  2. Published Print: 1 JUN 2005

ISBN Information

Print ISBN: 9780471474265

Online ISBN: 9780471719182

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CHAPTER TOOLS

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Keywords:

  • genetic linkage in humans;
  • dominance;
  • recessiveness;
  • segregation;
  • multiple alleles

Summary

This chapter contains sections titled:

  • Dominance, Recessiveness, and Segregation

  • Independent Assortment

  • Genetic Linkage

  • Constructing Genetic Maps

  • Chi-Square Distribution: Testing for Significance

  • Multiple Alleles

  • Human Genetics

  • Calculating Mendelian Frequencies

  • Detection and Estimation of Genetic Linkage in Humans

  • The Logarithm of the Likelihood Ratio Method of Linkage Analysis: LOD Score

  • Key Terms

  • Summary

  • References

  • Review Questions

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