Chapter 4. The Molecular Biology of the Gene

  1. Jack J. Pasternak

Published Online: 27 JAN 2005

DOI: 10.1002/0471719188.ch4

An Introduction to Human Molecular Genetics: Mechanisms of Inherited Diseases, Second Edition

An Introduction to Human Molecular Genetics: Mechanisms of Inherited Diseases, Second Edition

How to Cite

Pasternak, J. J. (2005) The Molecular Biology of the Gene, in An Introduction to Human Molecular Genetics: Mechanisms of Inherited Diseases, Second Edition, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471719188.ch4

Author Information

  1. University of Waterloo, Ontario, Canada

Publication History

  1. Published Online: 27 JAN 2005
  2. Published Print: 1 JUN 2005

ISBN Information

Print ISBN: 9780471474265

Online ISBN: 9780471719182

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Keywords:

  • DNA replication;
  • dominant mutations and genetic disorders;
  • decoding genetic information

Summary

This chapter contains sections titled:

  • Properties of Genetic Material

  • Structure of DNA

  • DNA Replication

  • Decoding Genetic Information: RNA and Protein

  • Translation

  • Regulation of mRNA Transcription

  • Hemoglobinopathies and Thalassemias: An Abundance of Mutations

  • Nucleotide Sequence Alteration: Mutation

  • Mutations of Structural Genes

  • Nomenclature for Mutations

  • Dominant Mutations and Genetic Disorders

  • Key Terms

  • Summary

  • References

  • Review Questions