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Cleaning and Normalization

  1. Geoffrey J. McLachlan,
  2. Kim-Anh Do,
  3. Christophe Ambroise

Published Online: 28 JAN 2005

DOI: 10.1002/047172842X.ch2

Book Title

Analyzing Microarray Gene Expression Data

Analyzing Microarray Gene Expression Data

Additional Information

How to Cite

McLachlan, G. J., Do, K.-A. and Ambroise, C. (2005) Cleaning and Normalization, in Analyzing Microarray Gene Expression Data, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/047172842X.ch2

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 21 JUL 2004

ISBN Information

Print ISBN: 9780471226161

Online ISBN: 9780471728429

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CHAPTER TOOLS

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Keywords:

  • normalization;
  • cleaning;
  • gene expression microarray data;
  • differential expression;
  • image processing

Summary

This chapter includes the following topics:

  • Introduction

  • Cleaning Procedures

  • Normalization and Plotting Procedures for Oligonucleotide Arrays

  • Normalization Methods for cDNA Microarray Data

  • SNOMAD

  • Transformations and Replication

  • Analysis of the Alon Data Set

  • Comparison of Normalization Strategies and Discussion

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