6. MALDI-TOF Mass Spectrometry of Intact Bacteria

  1. Charles L. Wilkins1 and
  2. Jackson O. Lay Jr.2
  1. Jackson O. Lay Jr. and
  2. Rohana Liyanage

Published Online: 3 JAN 2006

DOI: 10.1002/0471748641.ch6

Identification of Microorganisms by Mass Spectrometry, Volume 169

Identification of Microorganisms by Mass Spectrometry, Volume 169

How to Cite

Lay, J. O. and Liyanage, R. (2005) MALDI-TOF Mass Spectrometry of Intact Bacteria, in Identification of Microorganisms by Mass Spectrometry, Volume 169 (eds C. L. Wilkins and J. O. Lay), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471748641.ch6

Editor Information

  1. 1

    Department of Chemistry, University of Arkansas, Fayetteville, AR 72701, USA

  2. 2

    University of Arkansas, Fayetteville, AR 72701, USA

Author Information

  1. University of Arkansas, Fayetteville, AR 72701, USA

Publication History

  1. Published Online: 3 JAN 2006
  2. Published Print: 14 OCT 2005

Book Series:

  1. Chemical Analysis

Book Series Editors:

  1. J. D. Winefordner

ISBN Information

Print ISBN: 9780471654421

Online ISBN: 9780471748649

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Keywords:

  • whole-cell MALDI-TOF MS method;
  • sonication of bacteria;
  • MALDI-TOF MS spectra

Summary

This chapter contains sections titled:

  • Introduction

  • MALDI MS of Cellular Extracts

  • Taxonomy: From Isolates to Whole-Cell MALDI

  • Whole-Cell MALDI MS

  • Biology-Based Changes in Whole-Cell MALDI Spectra

  • Analysis of Mixtures

  • Experimental Approaches

  • Identification of Protein Markers

  • Detection of Target Proteins

  • Analysis of Clinical Isolates

  • Conclusions

  • References