15. Fatal Familial Insomnia

  1. Teofilo Lee-Chiong M.D.
  1. Charles A. Polnitsky

Published Online: 4 NOV 2005

DOI: 10.1002/0471751723.ch15

Sleep: A Comprehensive Handbook

Sleep: A Comprehensive Handbook

How to Cite

Polnitsky, C. A. (2005) Fatal Familial Insomnia, in Sleep: A Comprehensive Handbook (ed T. Lee-Chiong), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0471751723.ch15

Editor Information

  1. National Jewish Medical and Research Center, University of Colorado Health Sciences Center Denver, Colorado, USA

Author Information

  1. Regional Sleep Laboratory, Waterbury, Connecticut, USA

Publication History

  1. Published Online: 4 NOV 2005
  2. Published Print: 4 NOV 2005

ISBN Information

Print ISBN: 9780471683711

Online ISBN: 9780471751724



  • fatal familial insomnia (FFI);
  • prion molecular biology;
  • genetics of FFI


This chapter contains sections titled:

  • Introduction

  • Prion Molecular Biology

  • Mode of Dissemination

  • Genetics of FFI

  • History and Epidemiology of FFI

  • Clinical Presentation

  • Clinical Test Results

  • Clinicopathologic Implications about Sleep Regulation

  • Prevention and Treatment

  • Conclusion

  • References

  • Additional Reading