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Desmoplastic malignant melanoma (A rare variant of spindle cell melanoma)

  1. John Conlev MD,
  2. Raffaele Lattes MD,
  3. William Orr MD

Article first published online: 28 JUN 2006

DOI: 10.1002/1097-0142(1971)28:4<914::AID-CNCR2820280415>3.0.CO;2-E

Issue

Cancer

Cancer

Volume 28, Issue 4, pages 914–936, 1971

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How to Cite

Conlev, J., Lattes, R. and Orr, W. (1971), Desmoplastic malignant melanoma (A rare variant of spindle cell melanoma). Cancer, 28: 914–936. doi: 10.1002/1097-0142(1971)28:4<914::AID-CNCR2820280415>3.0.CO;2-E

Author Information

  1. Departments of Pathology, Division of Surgical Pathology, and the Head and Neck Service, Columbia-Presbyterian Medical Center and the College of Physicians and Surgeons of Columbia University, New York, N, Y.

Publication History

  1. Issue published online: 28 JUN 2006
  2. Article first published online: 28 JUN 2006
  3. Manuscript Received: 19 APR 1971

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Abstract

This is a detailed report of seven cases presenting a peculiar sequence of events which, starting from inconspicuous superficial melanotic lesions, generally located in the head and neck regions leads to the production of bulky subcutaneous tumefactions. These have the clinical and histologic appearance of locally invasive fibrous tumors. However, the elongated neoplastic cells are cytologically different from neoplastic fibroblasts, and these tumors behave as highly malignant stubbornly recurring and often metastasizing neoplasms. Some of the recurrences, as well as some of the metastases, are histologically acceptable as malignant melanoma of the more usual type. This appears to be a hitherto undescribed clinicopathologic entity, for which we suggest the term “desmoplastic malignant melanoma.”.

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