Polyps and diverticulosis of large bowel in autopsy population of Akita prefecture, compared with Miyagi. High risk for colorectal cancer in Japan

Authors

  • Eiichi Sato MD,

    Corresponding author
    1. Second Department of Pathology, Tohoku University School of Medicine, Sendai City, Japan
    • Department of Pathology, Tohoku University School of Medicine, 2–1 Seiryomachi, Sendai, Japan
    Search for more papers by this author
  • Akio Ouchi MD,

    1. Second Department of Pathology, Tohoku University School of Medicine, Sendai City, Japan
    Search for more papers by this author
  • Nobuaki Sasano MD,

    1. Second Department of Pathology, Tohoku University School of Medicine, Sendai City, Japan
    Search for more papers by this author
  • Takuzo Ishidate MD

    1. Second Department of Pathology, Tohoku University School of Medicine, Sendai City, Japan
    Search for more papers by this author
    • Department of Pathology, Akita University School of Medicine.


Abstract

A necropsy study of polypoid lesions and diverticula of the large bowel in the Japanese prefectures of Akita and Miyagi indicated that adenomatous polyps were more numerous in Akita (30%) than Miyagi (18.3%). They also were larger and showed more severe atypia in Akita. The sigmoid colon and rectum showed the most severe atypia in both prefectures. Hyperplastic polyps and diverticula were very uncommon in both prefectures. These results are discussed in relation to the different levels of risk to colorectal carcinoma in these prefectures and in Japanese migrants to Hawaii.

Ancillary