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Results of a 400-patient carcinoembryonic antigen second-look colorectal cancer study

  1. John Peter Minton MD†,*,
  2. James L. Hoehn MD,
  3. David M. Gerber MD,
  4. J. Shelton Horsley MD,
  5. David P. Connolly MD,
  6. Fayiz Salwan MD,
  7. William S. Fletcher MD,
  8. Anatolio B. Cruz Jr. MD,
  9. Frank G. Gatchell MD,
  10. Miguel Oviedo MD,
  11. Kenneth K. Meyer MD,
  12. Lasalle D. Leffall Jr. MD,
  13. Richard S. Berk MD,
  14. Peter A. Stewart BS,
  15. Susan E. Kurucz BS

Article first published online: 29 JUN 2006

DOI: 10.1002/1097-0142(19850315)55:6<1284::AID-CNCR2820550622>3.0.CO;2-B

Issue

Cancer

Cancer

Volume 55, Issue 6, pages 1284–1290, 15 March 1985

Additional Information

How to Cite

Minton, J. P., Hoehn, J. L., Gerber, D. M., Horsley, J. S., Connolly, D. P., Salwan, F., Fletcher, W. S., Cruz, A. B., Gatchell, F. G., Oviedo, M., Meyer, K. K., Leffall, L. D., Berk, R. S., Stewart, P. A. and Kurucz, S. E. (1985), Results of a 400-patient carcinoembryonic antigen second-look colorectal cancer study. Cancer, 55: 1284–1290. doi: 10.1002/1097-0142(19850315)55:6<1284::AID-CNCR2820550622>3.0.CO;2-B

Author Information

  1. Department of Surgery, The Ohio State University College of Medicine, Columbus, Ohio

  1. †

    American Cancer Society Professor of Clinical Oncology.

*The Ohio State University Hospitals, 410 West 10th Avenue (N-729), Columbus, OH 43210

Publication History

  1. Issue published online: 29 JUN 2006
  2. Article first published online: 29 JUN 2006
  3. Manuscript Accepted: 29 OCT 1984

Funded by

  • American Cancer Society, Ohio Division. Grant Number: CP-25

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Abstract

Four hundred patients with resectable colon and rectal cancers were operated on by 37 surgeons at 31 institutions. Patients were monitored with carcinoembryonic antigen (CEA) level determinations and clinical examinations. One hundred thirty patients had recurrences, and 75 were reoperated on, with 43 reoperations CEA-directed and 32 clinically directed. Two of 75 died within 1 month after the second operation. Twenty-two second-look patients remain free of disease 5 years after their second operaton. The highest resectability of recurrent cancer occurred in patients with a CEA level below 11 ng/ml in whom the CEA level was determined at intervals of 1 to 2 months. Cancer 55:1284-1290, 1985.

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