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Review
Molecular and cellular biology of avian somite development
Article first published online: 21 SEP 2000
DOI: 10.1002/1097-0177(2000)9999:9999<::AID-DVDY1057>3.0.CO;2-5
Copyright © 2000 Wiley-Liss, Inc.
1097-0177/asset/cover.gif?v=1&s=a30853283ce4b85446696e388141e1b70e2222b2 "Developmental Dynamics")
Additional Information
How to Cite
Stockdale, F. E., Nikovits Jr., W. and Christ, B. (2000), Molecular and cellular biology of avian somite development. Developmental Dynamics, 219: 304–321. doi: 10.1002/1097-0177(2000)9999:9999<::AID-DVDY1057>3.0.CO;2-5
Publication History
- Issue published online: 30 OCT 2000
- Article first published online: 21 SEP 2000
- Manuscript Accepted: 7 AUG 2000
- Manuscript Received: 13 JUN 2000
Funded by
- Deutsche Forschungsgemeinschaft. Grant Numbers: Ch 44/9-2, 44/12-1, 2, 3
- National Institutes of Health. Grant Numbers: AG-0822, HD-31956
- USDA. Grant Number: 00-03280
- Abstract
- Article
- References
- Cited By
Keywords:
- myotome;
- dermomyotome;
- sclerotome;
- segmental plate;
- somite;
- myogenesis;
- chondrogenesis;
- Wnt;
- Pax;
- Notch;
- BMP;
- EphA4;
- Paraxis
Abstract
Much of our understanding of early vertebrate embryogenesis derives from experimental work done with the chick embryo. Studies of the avian somite have played a key role in elucidating the developmental history of this important structure, the source of most muscle and bone in the organism. Here we review the development of the avian somite including morphological and molecular data on the origin of paraxial mesoderm, maturation of the segmental plate, specification and formation of somite compartments, and somite cell differentiation into cartilage and skeletal muscle. © 2000 Wiley-Liss, Inc.